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Home Antibody All anti-XPC antibodies
UltraMAB

Anti-XPC GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590624
  • Rabbit Polyclonal XPC Antibody
100ug 325 In Stock
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ELISA(1)

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration0.82mg/ml
Guaranteed Application *ELISA Suggested DilutionsELISA: 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens xeroderma pigmentosum, complementation group C (XPC), transcript variant 1
Alternative Namep125; RAD4; XP3; XPCC
Database LinkNP_004619
Entrez Gene 7508 Human
FunctionHuman XPC (Xeroderma pigmentosum group C) is a member of a family of proteins that has been shown to be involved in the repair of DNA via the nucleotide excision repair (NER) pathway. Specifically, XPC is believed to be a part of a heteromeric protein complex that is involved in the recognition of the DNA lesions during global genomic repair but not transcription-coupled repair. XPC may play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage processing enzymes. Defects in XPC are a cause of xeroderma pigmentosum complementation group C (XPC); also known as xeroderma pigmentosum III (XP3). XPC is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities.
Related PathwayDruggable Genome Nucleotide excision repair

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* OriGene provides validated application data and protocol, with money back guarantee.

ELISA Image
ELISA: XPC Antibody

 

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