Home Antibody All anti-TLE1 antibodies
Anti-TLE1 GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for TLE1 (NM_005077)
|DNA immunization. This antibody is specific for the Middle Region of the target protein.|
||WB 1:20000, ELISA 1:100-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) (TLE1)|
|ESG; ESG1; GRG1|
|TLE 1 is a transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. TLE 1 inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.|
Delta-Notch Signaling Pathway
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TLE1 (RC204037, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TLE1.