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Home Antibody All anti-CTLA4 antibodies
UltraMAB

Anti-CTLA4 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590611
  • Rabbit Polyclonal CTLA4 Antibody
50ug 325 In Stock
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(1)
IHC(4)
ELISA(1)
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Also for CTLA4 (NM_005214)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the entire range of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.1 mg/ml
Guaranteed Application *WB, ELISA, IHC Suggested Dilutions WB 1:20000, IHC 1:150,ELISA 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens cytotoxic T-lymphocyte-associated protein 4 (CTLA4), transcript variant 1
Alternative NameCD; CD152; CELIAC3; CTLA-4; GRD4; GSE; IDDM12
Database LinkNP_005205
Entrez Gene 1493 Human
FunctionThe lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. (1-4) However CD152 is thought to be a negative regulator of T cell activation (1-3) and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer1, and is relatively conserved among humans, mice and chickens. (2)
Related PathwayTransmembraneDruggable Genome Cell adhesion molecules (CAMs)T cell receptor signaling pathwayAutoimmune thyroid disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CTLA4 (RC210150, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CTLA4.
ELISA Image
ELISA: CTLA4 Antibody
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CTLA4 rabbit polyclonal antibody. (TA590611)
IHC Image
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-CTLA4 rabbit polyclonal antibody. (TA590611)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CTLA4 rabbit polyclonal antibody. (TA590611)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-CTLA4 rabbit polyclonal antibody. (TA590611)

 

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