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Home Antibody All anti-ARFGEF2 antibodies
UltraMAB

Anti-ARFGEF2 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590572
  • Rabbit Polyclonal ARFGEF2 Antibody
50ug 325 In Stock
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IHC(1)
IF(1)
ELISA(1)

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.14599
Guaranteed Application *ELISA, IHC, IF Suggested DilutionsELISA: 1:100-1:2000; IHC: 1:350; IF: 1:87
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) (ARFGEF2)
Alternative NameBIG2; dJ1164I10.1; PVNH2
Database LinkNP_006411
FunctionBIG2 promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF1/ARF5/ARF6 through replacement of GDP with GTP. ARFGEF2 plays an important role in vesicular and membrane trafficking from the trans-golgi network. It is also involved in the activation of ARFs (1,5, and 6) by accelerating replacement of bound GDP with GTP. It also acts as the activator of ADP-ribosylation factor GTPases that are essential for regulating vesicular traffic among intracellular organelles.
Related Pathway

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ELISA Image
ELISA: ARFGEF2 Antibody
IHC Image
Immunohistochemical staining of human pancreas shows strong cytoplasmic positivity in exocrine cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
IF Image
Immunofluorescent staining of human cell line U-251 MG shows no positivity.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.

 

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