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Home Antibody All anti-ASPM antibodies
UltraMAB

Anti-ASPM GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA590496
  • Rabbit Polyclonal ASPM Antibody
100ug $325 3 Weeks
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IHC(2)
IF(1)
ELISA(1)

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.03mg/ml
Guaranteed Application *ELISA, IHC, IF Suggested DilutionsELISA: 1:100-1:2000; IHC: 1:200; IF: 1:50
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens asp (abnormal spindle) homolog, microcephaly associated (Drosophila) (ASPM), transcript variant 1
Alternative NameASP; Calmbp1; MCPH5
Database LinkNP_060606
Entrez Gene 259266 Human
FunctionThe ASPM gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts (Bond et al., 2002). The mouse gene Aspm is expressed specifically in the primary sites of prenatal cerebral cortical neurogenesis.[supplied by OMIM]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

ELISA: ASPM Antibody
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Immunohistochemistry: ASPM Antibody - Most of the normal tissues displayed moderate cytoplasmic positivity which was occasionally accompanied with nuclear staining. Strong cytoplasmic staining was seen in gall bladder and in stomach while adrenal cortex, hepatocytes and bone marrow poietic cells also showed strong nuclear positivity. Neuronal and lymphoid tissues were generally weakly stained or negative. Malignant tissues exhibited weak to moderate cytoplasmic immunoreactivity. Malignant carcinoids, lymphomas, head & neck, thyroid, testis and urothelial cancers were mainly weakly stained or negative. Image and statement courtesy of the Human Protein Atlas (HPA).
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Immunohistochemical staining of human liver shows strong nuclear and cytoplasmic positivity in hepatocytes.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
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Immunofluorescent staining of human cell line U-2 OS shows positivity in plasma membrane & cytoplasm.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
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