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Home Antibody All anti-ULBP2 antibodies
UltraMAB

Anti-ULBP2 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590444
  • Rabbit Polyclonal ULBP2 Antibody
100ug 325 In Stock
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WB(1)
IHC(1)
ELISA(1)
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Also for ULBP2 (NM_025217)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the Middle Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.01mg/ml
Guaranteed Application *WB, ELISA, IHC Suggested DilutionsWB: 1:5000-1:20000; ELISA: 1:100-1:2000; IHC: 1:1500
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens UL16 binding protein 2 (ULBP2)
Alternative NameN2DL2; RAET1H
Database LinkNP_079493
FunctionULBP2 is a ligand for the NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transductionpathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface.
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 11; Lane 2: RT-4; Lane 3: U-251 MG; Lane 4: Human Plasma; Lane 5: Liver; Lane 6: TonsilThis validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
ELISA Image
ELISA: ULBP2 Antibody
IHC Image
Immunohistochemical staining of human stomach shows cytoplasmic positivity in a subset of inflammatory cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.

 

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