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Home Antibody All anti-CD276 antibodies

Anti-CD276 GAT Antibody Polyclonal

Generated by Genomic Immunization


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA590443 Rabbit Polyclonal CD276 Antibody 100ug $325 2 Weeks
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OriGene Data

ImmunogenDNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.11mg/ml
Guaranteed Application *ELISA, IHC, IF Suggested DilutionsELISA: 1:100-1:2000; IHC: 1:200; IF: 1:200
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens CD276 molecule (CD276), transcript variant 2
Alternative Name4Ig-B7-H3; B7-H3; B7H3; B7RP-2
Database LinkNP_079516
Entrez Gene 80381 Human
FunctionCostimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558).
Related PathwayTransmembraneDruggable Genome Cell adhesion molecules (CAMs)

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

ELISA: CD276 Antibody

IHC Image
Immunohistochemistry: CD276 Antibody - Most normal tissues displayed moderate cytoplasmic and occasional membranous immunoreactivity. Strong membranous expression was observed in the prostate gland. Basal layers of squamous epithelia showed moderate cytoplasmic positivity. Most cases of tumors demonstrated moderate cytoplasmic staining often combined with membranous immunoreactivity. Squamous cell carcinomas and adenocarcinomas of prostate and endometrium demonstrated strong membranous staining. A majority of cases in malignant lymphomas, stomach and pancreatic cancers were weakly stained or negative. Image and statement courtesy of the Human Protein Atlas (HPA).

IHC Image
Immunohistochemical staining of human prostate shows strong positivity in glandular cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.

IF Image
Immunofluorescent staining of human cell line U-251MG shows no positivity.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.


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