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Home Antibody All anti-CASP7 antibodies

Anti-CASP7 GAT Antibody Polyclonal

Generated by Genomic Immunization


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA590426 Rabbit Polyclonal Caspase 7 Antibody 100ug $325 In Stock
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Also for CASP7 (NM_033338)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman , Monkey , Mouse Concentration1.27153 mg/ml
Guaranteed Application *WB, ELISA, IHC Suggested Dilutions WB 1:5000~20000, IHC 1:150,ELISA 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens caspase 7, apoptosis-related cysteine peptidase (CASP7), transcript variant d
Alternative NameCASP-7; CMH-1; ICE-LAP3; LICE2; MCH3
Database LinkNP_203124
Entrez Gene 840 Human
Entrez Gene 12369 Mouse
Entrez Gene 697633 Monkey
FunctionCaspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase-9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
Related PathwayProteaseDruggable Genome ApoptosisAlzheimer's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CASP7 (RC221589, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CASP7.

WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CASP7 polyclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

ELISA: Caspase 7 Antibody - Affinity Purified

IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-CASP7 rabbit polyclonal antibody. (TA590426)

IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-CASP7 rabbit polyclonal antibody. (TA590426)


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