Home Antibody All anti-KLK7 antibodies
Anti-KLK7 GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for KLK7 (NM_139277)
|DNA immunization. This antibody is specific for the Middle Region of the target protein.|
|ELISA, IHC, IF
||WB: 1:500; ELISA: 1:100-1:2000; IHC: 1:600; IF: 1:150
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens kallikrein-related peptidase 7 (KLK7), transcript variant 2|
|hK7; PRSS6; SCCE|
|Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.|
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Immunohistochemical staining of human bone marrow shows strong cytoplasmic and nuclear positivity in a subset of bone marrow poietic cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
Immunofluorescent staining of human cell line A-431 shows positivity in nucleus but not nucleoli.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.