Home Antibody All anti-KLK11 antibodies
Anti-KLK11 GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for KLK11 (NM_144947)
|DNA immunization. This antibody is specific for the Middle Region of the target protein.|
|ELISA, IHC, IF
||ELISA: 1:100-1:2000; IHC: 1:650; IF: 1:162
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens kallikrein-related peptidase 11 (KLK11), transcript variant 2|
Entrez Gene 11012 Human
|Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of hK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.|
|Secreted ProteinProteaseDruggable Genome |
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Immunohistochemical staining of human salivary gland shows strong cytoplasmic and membranous positivity in ducts.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus but not nucleoli.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.