Home Antibody All anti-CSNK2A1 antibodies
Anti-CSNK2A1 GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for CSNK2A1 (NM_177559)
|DNA immunization. This antibody is specific for the C Terminus Region of the target protein.|
|ELISA, IHC, IF
||ELISA: 1:100-1:2000; IHC: 1:250; IF: 1:62
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens casein kinase 2, alpha 1 polypeptide (CSNK2A1), transcript variant 1|
|CK2A1; CKII; CSNK2A3|
|CKII is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. The kinase exists as a tetramer and is composed of an alpha, an alpha prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The gene for this protein is found on chromosome 20, but a related transcribed pseudogene is found on chromosome 11. Three transcript variants have been found, encoding two different isoforms. Protein kinase CKII is recognized as one of the key cellular signals for cell growth and proliferation; it also has an important role in apoptosis.|
Wnt Signaling Pathway
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Immunohistochemical staining of human hippocampus shows strong nuclear and cytoplasmic positivity in neuronal cells.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
Immunofluorescent staining of human cell line A-431 shows positivity in nucleus but not nucleoli.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.