Home Antibody All anti-CSF3R antibodies
Anti-CSF3R GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for CSF3R (NM_156039)
|DNA immunization. This antibody is specific for the Middle Region of the target protein.|
|WB, ELISA, IHC
||WB: 1:5000-1:20000; ELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:10-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens colony stimulating factor 3 receptor (granulocyte) (CSF3R), transcript variant 3|
|The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Four transcript variants encoding four different isoforms have been found for this gene, with three of the isoforms being membrane-bound and the other being secreted and soluble. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.|
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Jak-STAT signaling pathway
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Western Blot: GCSF Receptor Antibody - Samples: Lane 1: Marker: 250, 130, 95, 72, 55, 36, 28, 17, 11 / Lane 2: RT-4 / Lane 3: U-251MG sp / Lane 4: Human Plasma / Lane 5: Liver / Lane 6: Tonsil; Target weight: 95, 92, 87, 85 (splice variants)
ELISA: GCSF Receptor Antibody - Affinity Purified
Immunohistochemistry: GCSF Receptor Antibody - Most normal tissues were negative. Trophoblastic cells in placenta expressed strong cytoplasmic immunoreactivity. Myocardium, neuronal cells of cerebral cortex and Leydig cells showed moderate positivity. Among malignancies, most cancers were negative except for few adenocarcinomas of endometrium and one case of urothelial cancer that displayed moderate membranous staining in a fraction of cells. Image and statement courtesy of the Human Protein Atlas (HPA).