Home Antibody All anti-KRT23 antibodies
Anti-KRT23 GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for KRT23 (NM_015515)
|DNA immunization. This antibody is specific for the C Terminus Region of the target protein (NM_015515).|
|WB, ELISA, IHC
||WB: 1:5000-1:20000; ELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:10-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens keratin 23, type I (KRT23), transcript variant 1|
|CK23; HAIK1; K23|
Entrez Gene 25984 Human
|The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.|
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Western Blot: KRT23 Antibody - Samples: Lane 1, Marker: 250, 130, 95, 72, 55, 36, 28, 17, 11 Lane 2, RT-4 Lane 3, U-251MG sp Lane 4, Human Plasma Lane 5, Liver Lane 6, Tonsil , Target weight: 48, 4 (splice variants) Validation score: 2 Validation description: Supportive - Band of predicted size in kDa (+/-20%) with additional bands present.
Immunohistochemistry: KRT23 Antibody - Normal glandular cells showed moderate cytoplasmic immunoreactivity while most other cell types were weakly stained or negative. Exocrine pancreas, placental trophoblasts, adrenal cortical cells and Leydig cells in testis revealed strong positivity. A majority of malignant cells displayed moderate cytoplasmic immunoreactivity. Thyroid cancers and few cases of colorectal cancers revealed strong positivity. Most skin cancers, malignant lymphomas and gliomas were negative. Image and statement courtesy of the Human Protein Atlas (HPA). View all of the IHC expression profiles performed by the Human Protein Atlas.