Home Antibody All anti-PDGFRB antibodies
Anti-PDGFRB GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for PDGFRB (NM_002609)
|DNA immunization. This antibody is specific for the N Terminus Region of the target protein.|
||WB: 1:5000-1:20000; ELISA: 1:100-1:2000; IHC: 1:10-1:2000; IHC-P 1:250-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens platelet-derived growth factor receptor, beta polypeptide (PDGFRB)|
|CD140B; IBGC4; IMF1; JTK12; PDGFR; PDGFR-1; PDGFR1|
Entrez Gene 5159 Human
|Human platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-alpha and PDGF receptor-beta. PDGF receptor-beta can only bind two specific PDGF isoforms, PDGF-beta and PDGF-delta (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.|
|Protein KinaseES Cell Differentiation/IPSTransmembraneDruggable Genome MAPK signaling pathwayCalcium signaling pathwayCytokine-cytokine receptor interactionFocal adhesionGap junctionRegulation of actin cytoskeletonMore Pathways >> |
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.