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Home Antibody All anti-KISS1 antibodies
UltraMAB

Anti-KISS1 GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590117
  • Rabbit Polyclonal KISS1 Antibody
50ug 325 In Stock
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IHC(1)
IF(1)
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Also for KISS1 (NM_002256)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDNA immunization. This antibody was made against a protein fragment from the entire range of the protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.03869
Guaranteed Application *IHC, IF Suggested DilutionsELISA: 1:100-1:2000; IHC: 1:450; IF: 1:112
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens KiSS-1 metastasis-suppressor (KISS1)
Alternative NameHH13; KiSS-1
Database LinkNP_002247
FunctionKiSS-1 gene encodes metastin, also known as kisspeptin or KiSS-1 peptide, which binds to a G protein-coupled receptor GPR54. KiSS-1 is dominantly expressed in brain (e.g. anteroventral periventricular nucleus, AVPV arcuate nucleus, ARC), placenta, and pancreas, etc. Metastin plays an important role in regulating the GnRH secretion in brain and MMP-9 expression in placenta, which is associated with development of puberty and sex maturation (e.g. Idiopathic hypogonadotropic hypogonadism, IHH) as well as placentation (e.g. pre-eclampsia), respectively. Metastin was originally discovered as a tumor metastasis suppressor (e.g. melanoma, breastcancer).
Related Pathway
Signaling by GPCR

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IHC Image
Immunohistochemical staining of human placenta shows strong cytoplasmic positivity in trophoblasts.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
IF Image
Immunofluorescent staining of human cell line U-251 MG shows positivity in nucleoli & cytoplasm.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.

 

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