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Home Antibody All anti-HTR2B antibodies
UltraMAB

Anti-HTR2B GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA590053 Rabbit Polyclonal 5HT2B Receptor Antibody 100ug $325 In Stock
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WB(1)
IHC(4)
IF(1)
ELISA(1)

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the Middle Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.2mg/ml
Guaranteed Application *WB, ELISA, IHC, IF Suggested DilutionsWB: 1:100-1:2000; ELISA: 1:100-1:2000; IHC: 1:1100
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled (HTR2B)
Alternative Name5-HT(2B); 5-HT2B
Database LinkNP_000858
Entrez Gene 3357 Human
FunctionMultiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.[supplied by OMIM]
Related PathwayTransmembraneDruggable Genome Calcium signaling pathwayNeuroactive ligand-receptor interactionGap junction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western Blot: 5HT2B Receptor Antibody - Malignant lymphomas and gliomas were either negative or weakly cytoplasmic stained. Image (malignant lymphoma) was provided courtesy of the Swedish Human Proteome Resource (HPR) Center.
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ELISA: 5HT2B Receptor Antibody
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Immunohistochemistry: 5HT2B Receptor Antibody - IHC using anti HTR2B SEQer antibody
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Immunohistochemistry: 5HT2B Receptor Antibody - Most normal and malignant cells showed a moderate or strong cytoplasmic staining. Malignant lymphomas and gliomas were either negative or weakly cytoplasmic stained. Image (malignant lymphoma) was provided courtesy of the Swedish Human Proteome Resource (HPR) Center.
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Immunohistochemistry-Paraffin: 5HT2B Receptor Antibody - B = Total human brain extract (5ug). P = Total human placenta extract (5ug). T = Total human breast tumor extract (5ug). The Genomic Antibodies stock was 1mg/ml. The blot was probed with Genomic Antibodies overnight. (1:10,000), washed, probed with goat anti rabbit-HRP conjugate at 1:5000 dilution, washed and developed with chemiluminescence (film 5-30sec exposures).
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Immunohistochemical staining of human liver shows strong cytoplasmic and nuclear positivity in hepatocytes.This validation was performed by Protein Atlas and the presentation of data is for informational purposes only.
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Immunocytochemistry/Immunofluorescence: 5HT2B Receptor Antibody - Confocal immunofluorescent analysis of HeLa cells using LSD1 (C69G12) Rabbit mAb (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).
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