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Home Antibody All anti-VTN antibodies
UltraMAB

Anti-VTN GAT Antibody Polyclonal

Generated by Genomic Immunization

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA590043
  • Rabbit Polyclonal Vitronectin Antibody
100ug 325 In Stock
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ELISA(1)
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Also for VTN (NM_000638)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the N Terminus Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration1.08686
Guaranteed Application *ELISA Suggested DilutionsWB: 1:5000-1:20000; ELISA: 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens vitronectin (VTN)
Alternative NameV75; VN; VNT
Database LinkNP_000629
FunctionVitronectin, a 75 kDa polypeptide along with a 10 kDa fragment, is a glycoprotein present on most cell surfaces, in extracellular fluids and plasma (1). Vitronectin promotes cellular adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpin serine protease inhibitors (2). As a member of the integrin family, Vitronectin contains the cell binding sequence arg gly asp (RGD), first found in fibronectin, and serves as a cell-to-substrate adhesion molecule (3). Vitronectin acts as an inhibitor of the complement cascade by binding to the C5b9 complex and it has also been shown to have has a novel and direct role in self-senescent-self intercellular recognition leading to macrophage phagocytosis of cells undergoing apoptosis (4).
Related Pathway
Focal Adhesion
Senescence and Autophagy

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ELISA Image
ELISA: Vitronectin Antibody - Affinity Purified

 

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