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Anti-UNC13D TRUEMAB Antibody Clone 1F4
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for UNC13D (NM_199242)
|Full length human recombinant protein of human UNC13D(NP_954712) produced in HEK293T cell.|
|| WB 1:200~1000,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens unc-13 homolog D (C. elegans) (UNC13D)|
|FHL3; HLH3; HPLH3; Munc13-4|
|This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder. [provided by RefSeq, Jul 2008]. |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UNC13D (RC209141, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-UNC13D.