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Home Antibody All anti-FGG antibodies

Anti-FGG TRUEMAB Antibody Clone OTI4D3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA507150 FGG mouse monoclonal antibody, clone OTI4D3 (formerly 4D3) 100ul $325 In Stock
LC400173 FGG HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF507150 Carrier-free (glycerol/BSA-free) FGG mouse monoclonal antibody, clone OTI4D3 (formerly 4D3) 100ug $450 3-4 Days
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WB(1)
IHC(2)

OriGene Data

ImmunogenFull length human recombinant protein of human FGG(NP_000500) produced in HEK293T cell.
Clone NameClone OTI4D3 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:4000, IHC 1:150,
Predicted MW Explanation 46.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens fibrinogen gamma chain (FGG), transcript variant gamma-A
Alternative Namefibrinogen, gamma chain; fibrinogen, gamma polypeptide; fibrinogen gamma chain
Database LinkNP_000500
Entrez Gene 2266 Human
FunctionThe protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul
Related PathwaySecreted ProteinTransmembraneDruggable Genome Complement and coagulation cascades

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FGG (RC202770, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FGG.
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Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-FGG mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA507150)
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-FGG mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA507150)
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