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Home Antibody All anti-FGG antibodies

Anti-FGG TRUEMAB Antibody Clone 4D3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA507150
  • FGG mouse monoclonal antibody,clone 4D3
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400173) , 20ug Explanation
100ul 325 In Stock
CF507150
  • Carrier-free (glycerol/BSA-free) FGG mouse monoclonal antibody,clone 4D3
100ug $450 3-4 Days
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WB(1)
IHC(2)

OriGene Data

ImmunogenFull length human recombinant protein of human FGG(NP_000500) produced in HEK293T cell.
Clone NameClone 4D3 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:4000, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens fibrinogen gamma chain (FGG), transcript variant gamma-A
Alternative Namefibrinogen, gamma chain; fibrinogen, gamma polypeptide; fibrinogen gamma chain
Database LinkNP_000500
Entrez Gene 2266 Human
FunctionThe protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul
Related PathwaySecreted ProteinTransmembraneDruggable Genome Complement and coagulation cascades

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY FGG (RC202770, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-FGG.
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-FGG mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA507150)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-FGG mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA507150)

 

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