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Home Antibody All anti-PMS2 antibodies

Anti-PMS2 TRUEMAB Antibody Clone OTI4B7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA506683 PMS2 mouse monoclonal antibody, clone OTI4B7 (formerly 4B7) 100ul $325 In Stock
LC424658 PMS2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506683 Carrier-free (BSA/glycerol-free) PMS2 mouse monoclonal antibody, clone OTI4B7 (formerly 4B7) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(4)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human PMS2(NP_000526) produced in HEK293T cell.
Clone NameClone OTI4B7 IsotypeIgG2b
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:500, IHC 1:150, IF: 1:100
Predicted MW Explanation 95.6 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens PMS2 postmeiotic segregation increased 2 (S. cerevisiae) (PMS2), transcript variant 1
Alternative NameHNPCC4; PMS2CL; PMSL2
Database LinkNP_000526
Entrez Gene 5395 Human
FunctionThis gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008].
Related PathwayDruggable Genome Mismatch repair

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMS2 (RC210880, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PMS2.
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PMS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506683)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PMS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506683)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PMS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506683)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PMS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506683)
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Immunofluorescent staining of HeLa cells using anti-PMS2 mouse monoclonal antibody (TA506683).
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