OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-TGFB1 antibodies

Anti-TGFB1 TRUEMAB Antibody Clone 1E12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA506585
  • TGFB1 mouse monoclonal antibody,clone 1E12
100ul 325 In Stock
CF506585
  • Carrier-free (BSA/glycerol-free) TGFB1 mouse monoclonal antibody,clone 1E12
100ug $450 8-10 Days
Add to Shopping Cart
WB(1)
IF(2)
FC(1)
spacer
Also for TGFB1 (NM_000660)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human TGFB1(NP_000651) produced in HEK293T cell.
Clone NameClone 1E12 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF, FC Suggested Dilutions WB 1:1000, IF 1:100, FLOW 1:50,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens transforming growth factor, beta 1 (TGFB1)
Alternative NameCED; DPD1; LAP; TGFB; TGFbeta
Database LinkNP_000651
Entrez Gene 7040 Human
FunctionThis gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct
Related PathwaySecreted ProteinES Cell Differentiation/IPSTranscription FactorsDruggable Genome MAPK signaling pathwayCytokine-cytokine receptor interactionCell cycleTGF-beta signaling pathwayPathways in cancerColorectal cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TGFB1 (RC200973, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TGFB1.
IF Image
Anti-TGFB1 mouse monoclonal antibody (TA506585) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TGFB1(RC200973).
IF Image
Immunofluorescent staining of HeLa cells using anti-TGFB1 mouse monoclonal antibody (TA506585).
FC Image
Flow cytometric Analysis of SF295 cells, using anti-TGFB1 antibody(TA506585),(Red), compared to a nonspecific negative control antibody,(Blue).

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title