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Home Antibody All anti-TGFB1 antibodies

Anti-TGFB1 TRUEMAB Antibody Clone OTI1E12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA506585 TGFB1 mouse monoclonal antibody, clone OTI1E12 (formerly 1E12) 100ul 325
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CF506585 Carrier-free (BSA/glycerol-free) TGFB1 mouse monoclonal antibody, clone OTI1E12 (formerly 1E12) 100ug $450 3 Days
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Also for TGFB1 (NM_000660)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human TGFB1(NP_000651) produced in HEK293T cell.
Clone NameClone OTI1E12 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF, FC Suggested Dilutions WB 1:1000, IF 1:100, FLOW 1:50,
Predicted MW Explanation 28.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens transforming growth factor, beta 1 (TGFB1)
Alternative NameCED; DPD1; LAP; TGFB; TGFbeta
Database LinkNP_000651
Entrez Gene 7040 Human
FunctionThis gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct
Related PathwaySecreted ProteinES Cell Differentiation/IPSTranscription FactorsDruggable Genome MAPK signaling pathwayCytokine-cytokine receptor interactionCell cycleTGF-beta signaling pathwayPathways in cancerColorectal cancerMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TGFB1 (RC200973, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TGFB1.
Anti-TGFB1 mouse monoclonal antibody (TA506585) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TGFB1(RC200973).
Immunofluorescent staining of HeLa cells using anti-TGFB1 mouse monoclonal antibody (TA506585).
Flow cytometric Analysis of SF295 cells, using anti-TGFB1 antibody(TA506585),(Red), compared to a nonspecific negative control antibody,(Blue).


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