Home Antibody All anti-PTPRC antibodies
Anti-PTPRC TRUEMAB Antibody Clone OTI3D1
TrueMAB Antibodies - Made against Authentic Protein Antigens
Write Review & Get Rewarded
Write a review and get rewarded!
Review this antibody and earn an OriGene coupon or Amazon giftcard
Follow these easy steps to reward yourself:
- Sign in to your account, or register for a new account;
- Write a review;
- Receive a coupon or giftcard once your review is accepted.
Click the button to start writing a review
Also for PTPRC (NM_002838)
|Full length human recombinant protein of human PTPRC(NP_002829) produced in HEK293T cell.|
|WB, IHC, FC
||WB 1:4000, IHC 1:500, FLOW 1:50,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens protein tyrosine phosphatase, receptor type C (PTPRC), transcript variant 1|
|B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200|
Entrez Gene 5788 Human
|The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012].|
|ES Cell Differentiation/IPSTransmembranePhosphataseDruggable Genome Cell adhesion molecules (CAMs)T cell receptor signaling pathwayFc gamma R-mediated phagocytosisPrimary immunodeficiency|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
HEK293T cells lysate (5 ug, left lane) and full length human recombinant protein of human PTPRC(NP_002829) produced in HEK293T cell (5 ug, right lane)were separated by SDS-PAGE and immunoblotted with anti-PTPRC.
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-PTPRC mouse monoclonal antibody. (TA506563; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Immunohistochemical staining of paraffin-embedded Human lymphoma tissue using anti-PTPRC mouse monoclonal antibody. (TA506563; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
Flow cytometric Analysis of living Jurkat cells,using anti-PTPRC antibody(TA506563),(Red),compared to IgG isotype control,(green) and PBS (blue).