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Home Antibody All anti-TNF antibodies

Anti-TNF CONJUGATED Antibody Clone OTI1C1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA506513FM TNF mouse monoclonal antibody,clone 1C1, DyLight 594 conjugated 100ul $600 1-2 Weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human TNF(NP_000585) produced in HEK293T cell.
Clone NameClone OTI1C1 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application * Suggested Dilutions
Predicted MW Explanation 25.5 kDa
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens tumor necrosis factor (TNF)
Alternative NameDIF; TNF-alpha; TNFA; TNFSF2
Database LinkNP_000585
FunctionThis gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008].
Related PathwaySecreted ProteinTransmembraneTranscription FactorsDruggable Genome MAPK signaling pathwayCytokine-cytokine receptor interactionApoptosisTGF-beta signaling pathwayToll-like receptor signaling pathwayNOD-like receptor signaling pathwayMore Pathways >>

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