Anti-TP73 Antibody, Clone 2H5

Also for TP73 (NM_005427)

OriGene Data

Immunogen	Human recombinant protein fragment corresponding to amino acids 167-409 of human TP73 (NP_005418) produced in HEK293T cell.
Clone Name	Clone 2H5	Isotype	IgG1
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC, IF	Suggested Dilutions	WB 1:4000, IHC 1:150, IF 1:100,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens tumor protein p73 (TP73), transcript variant 1
Alternative Name	P73
Database Link	NP_005418
Function	This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb
Related Pathway	Apoptosis TGF Beta Signaling Pathway

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WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TP73 (RC220864, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TP73.

IHC Image

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-TP73 mouse monoclonal antibody. (TA506470)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-TP73 mouse monoclonal antibody. (TA506470)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-TP73 mouse monoclonal antibody. (TA506470)

IHC Image

Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-TP73 mouse monoclonal antibody. (TA506470)

IF Image

Anti-TP73 mouse monoclonal antibody (TA506470) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TP73(RC220864).

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
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PE
FITC
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DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-TP73 TrueMAB Antibody Clone 2H5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data