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Home Antibody All anti-IL1B antibodies

Anti-IL1B TRUEMAB Antibody Clone 3E1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (2) Related Products Product Documents
SKU Description Amount Price Availability*  
TA506443
  • IL1B mouse monoclonal antibody,clone 3E1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400196) , 20ug Explanation
100ul
30ul
379 In Stock
CF506443
  • Carrier-free (BSA/glycerol-free) IL1B mouse monoclonal antibody,clone 3E1
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(1)
IHC(1)
IF(1)
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Also for IL1B (NM_000576)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human IL1B(NP_000567) produced in HEK293T cell.
Clone NameClone 3E1 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:1000~4000, IHC 1:150, IF 1:100,
Predicted MW Explanation 30.6 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens interleukin 1, beta (IL1B)
Alternative NameIL-1; IL1-BETA; IL1F2
Database LinkNP_000567
Entrez Gene 3553 Human
FunctionThe protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].
Related PathwaySecreted ProteinDruggable Genome MAPK signaling pathwayCytokine-cytokine receptor interactionApoptosisToll-like receptor signaling pathwayNOD-like receptor signaling pathwayCytosolic DNA-sensing pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IL1B (RC202079, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IL1B.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-IL1B mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506443)
IF Image
Anti-IL1B mouse monoclonal antibody (TA506443) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IL1B(RC202079).

 

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