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Home Antibody All anti-PDGFRB antibodies

Anti-PDGFRB TRUEMAB Antibody Clone 1D2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA506233
  • PDGFRB mouse monoclonal antibody,clone 1D2
100ul 325 In Stock
CF506233
  • Carrier-free (BSA/glycerol-free) PDGFRB mouse monoclonal antibody,clone 1D2
100ug $450 8-10 Days
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WB(1)
IF(2)
FC(1)
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Also for PDGFRB (NM_002609)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PDGFRB(NP_002600) produced in HEK293T cell.
Clone NameClone 1D2 IsotypeIgG2a
Species ReactivityHuman Concentration1.00mg/ml
Guaranteed Application *WB, IF, FC Suggested Dilutions WB 1:2000, IF 1:100, FLOW 1:50,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens platelet-derived growth factor receptor, beta polypeptide (PDGFRB)
Alternative NameCD140B; IBGC4; IMF1; JTK12; PDGFR; PDGFR-1; PDGFR1
Database LinkNP_002600
FunctionThis gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008].
Related Pathway
Cytokine-cytokine receptor interaction
Focal Adhesion
MAPK signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDGFRB (RC206377, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDGFRB.
IF Image
Anti-PDGFRB mouse monoclonal antibody (TA506233) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDGFRB(RC206377).
IF Image
Immunofluorescent staining of HeLa cells using anti-PDGFRB mouse monoclonal antibody (TA506233).
FC Image
Flow cytometric Analysis of SF295 cells, using anti-PDGFRB antibody(TA506233),(Red), compared to a nonspecific negative control antibody,(Blue).

 

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