OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-BCL2L1 antibodies

Anti-BCL2L1 TRUEMAB Antibody Clone 2D1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA506188
  • BCL2L1 mouse monoclonal antibody,clone 2D1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403363) , 20ug Explanation
100ul 325 In Stock
CF506188
  • Carrier-free (BSA/glycerol-free) BCL2L1 mouse monoclonal antibody,clone 2D1
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
Add to Shopping Cart
spacer
WB(1)
IHC(4)
spacer
Also for BCL2L1 (NM_138578)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human BCL2L1(NP_612815) produced in HEK293T cell.
Clone NameClone 2D1 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:1000, IHC 1:150,
Predicted MW Explanation 25.9 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens BCL2-like 1 (BCL2L1), transcript variant 1
Alternative NameBcl-X; bcl-xL; BCL-XL/S; bcl-xS; BCL2L; BCLX; BCLXL; BCLXS; PPP1R52
Database LinkNP_612815
Entrez Gene 598 Human
FunctionThe protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008].
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome ApoptosisJak-STAT signaling pathwayAmyotrophic lateral sclerosis (ALS)Pathways in cancerPancreatic cancerChronic myeloid leukemiaMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY BCL2L1 (RC201314, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-BCL2L1.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-BCL2L1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506188)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506188)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-BCL2L1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506188)
IHC Image
Immunohistochemical staining of paraffin-embedded Human bladder tissue using anti-BCL2L1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506188)

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title