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Anti-ENG CONJUGATED Antibody Clone OTI8A1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA506170S ENG (CD105) mouse monoclonal antibody, Clone 8A1 30ul $120 In Stock
CF506170 Carrier-free (BSA/glycerol-free) ENG mouse monoclonal antibody, clone OTI8A1 (formerly 8A1) 30ulug $450 3 Days
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OriGene Data

ImmunogenFull length human recombinant protein of human ENG(NP_000109) produced in HEK293T cell.
Clone NameClone OTI8A1 IsotypeIgG2b
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration1 mg/ml
Guaranteed Application * Suggested Dilutions
Predicted MW Explanation 65 kDa
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens endoglin (ENG), transcript variant 2
Alternative NameEND; HHT1; ORW1
Database LinkNP_000109
FunctionThis gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome

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