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Home Antibody All anti-PTK2 antibodies

Anti-PTK2 TRUEMAB Antibody Clone 4A8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA506161
  • PTK2 (FAK) mouse monoclonal antibody, Clone 4A8
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403521) , 20ug Explanation
100ul 325 In Stock
CF506161
  • Carrier-free (BSA/glycerol-free) PTK2 mouse monoclonal antibody,clone 4A8
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(1)
IHC(4)
IF(2)
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Also for PTK2 (NM_153831)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PTK2(NP_722560) produced in HEK293T cell.
Clone NameClone 4A8 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:4000, IHC 1:150, IF 1:100,
Predicted MW Explanation 119.1 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens protein tyrosine kinase 2 (PTK2), transcript variant 1
Alternative NameFADK; FAK; FAK1; FRNK; p125FAK; pp125FAK; PPP1R71
Database LinkNP_722560
Entrez Gene 5747 Human
FunctionThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010].
Related PathwayProtein KinaseDruggable Genome ErbB signaling pathwayChemokine signaling pathwayAxon guidanceVEGF signaling pathwayFocal adhesionLeukocyte transendothelial migrationMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTK2 (RC219839, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTK2.
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PTK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506161)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PTK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506161)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-PTK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506161)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-PTK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506161)
IF Image
Anti-PTK2 mouse monoclonal antibody (TA506161) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PTK2(RC219839).
IF Image
Immunofluorescent staining of HeLa cells using anti-PTK2 mouse monoclonal antibody (TA506161).

 

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