Anti-DNM1L Antibody, Clone 4F6

Also for DNM1L (NM_012062)

OriGene Data

Immunogen	Full length human recombinant protein of human DNM1L(NP_036192) produced in HEK293T cell.
Clone Name	Clone 4F6	Isotype	IgG2b
Species Reactivity	Human , Dog , Rat , Monkey , Mouse	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB 1:200~4000, IHC 1:150,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens dynamin 1-like (DNM1L), transcript variant 1
Alternative Name	DLP1; DRP1; DVLP; DYMPLE; DYNIV-11; EMPF; HDYNIV; VPS1
Database Link	NP_036192
Function	The protein encoded by this gene is a member of the dynamin superfamily of GTPases. Members of the dynamin-related subfamily, including the S. cerevisiae proteins Dnm1 and Vps1, contain the N-terminal tripartite GTPase domain but do not have the pleckstrin homology or proline-rich domains. This protein establishes mitochondrial morphology through a role in distributing mitochondrial tubules throughout the cytoplasm. The gene has 3 alternatively spliced transcripts encoding different isoforms. These transcripts are alternatively polyadenylated. [provided by RefSeq, Jul 2008].
Related Pathway

* Shipping is in business days

* OriGene provides validated application data and protocol, with money back guarantee.

WB Image

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DNM1L (RC221708, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DNM1L.

WB Image

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-DNM1L monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-DNM1L mouse monoclonal antibody. (TA506153)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-DNM1L mouse monoclonal antibody. (TA506153)

IHC Image

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-DNM1L mouse monoclonal antibody. (TA506153)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-DNM1L mouse monoclonal antibody. (TA506153)

IHC Image

Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-DNM1L mouse monoclonal antibody. (TA506153)

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

HRP
Biotin
PE
FITC
DyLight® 488
DyLight® 550
DyLight® 594
DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Anti-DNM1L TrueMAB Antibody Clone 4F6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data