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Home Antibody All anti-ERG antibodies

Anti-ERG TRUEMAB Antibody Clone4H7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA506076
  • ERG mouse monoclonal antibody,clone 4H7
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403650) , 20ug
100ul 325 In Stock
CF506076
  • Carrier-free (BSA/glycerol-free) ERG mouse monoclonal antibody,clone 4H7
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(3)
IF(1)
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Also for ERG (NM_182918)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human ERG(NP_891548) produced in HEk293T cell.
Clone NameClone4H7 IsotypeIgG1
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:2000, IHC 1:150, IF 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens v-ets avian erythroblastosis virus E26 oncogene homolog (ERG), transcript variant 1
Alternative Nameerg-3; p55
Database LinkNP_891548
FunctionThis gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jan
Related Pathway

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WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ERG (RC208093, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ERG.
IHC Image
Immunohistochemical staining of paraffin-embedded Human Ovary tissue using anti-ERG mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA506076)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-ERG mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA506076)
IHC Image
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-ERG mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA506076)
IF Image
Anti-ERG mouse monoclonal antibody (TA506076) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ERG(RC208093).

 

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