Home Antibody All anti-MAPK9 antibodies
Anti-MAPK9 TRUEMAB Antibody Clone 4D1
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for MAPK9 (NM_139068)
|Full length human recombinant protein of human MAPK9(NP_620707) produced in HEK293T cell.|
|Human , Dog , Mouse
|WB, IHC, IF
|| WB 1:200~2000, IHC 1:150, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens mitogen-activated protein kinase 9 (MAPK9), transcript variant JNK2-a1|
|JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; p54a; p54aSAPK; PRKM9; SAPK; SAPK1a|
Entrez Gene 5601 Human
Entrez Gene 26420 Mouse
Entrez Gene 474652 Dog
|The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]. |
|Protein KinaseES Cell Differentiation/IPSDruggable Genome MAPK signaling pathwayErbB signaling pathwayWnt signaling pathwayFocal adhesionToll-like receptor signaling pathwayNOD-like receptor signaling pathwayMore Pathways >> |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MAPK9 (RC207608, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MAPK9.
Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-MAPK9 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-MAPK9 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505910)
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-MAPK9 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA505910)
Anti-MAPK9 mouse monoclonal antibody (TA505910) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK9(RC207608).