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Home Antibody All anti-COPS6 antibodies

Anti-COPS6 TRUEMAB Antibody Clone OTIH4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA505755 COPS6 mouse monoclonal antibody, clone OTIH4 (formerly H4) 100ul $325 In Stock
LC416378 COPS6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF505755 Carrier-free (BSA/glycerol-free) COPS6 mouse monoclonal antibody, clone OTIH4 (formerly H4) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(2)
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Also for COPS6 (NM_006833)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 58-327 of human COPS6(NP_006824) produced in E.coli
Clone NameClone OTIH4 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB Suggested Dilutions WB 1:2000,
Predicted MW Explanation 36 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens COP9 signalosome subunit 6 (COPS6)
Alternative NameCSN6; MOV34-34KD
Database LinkNP_006824
Entrez Gene 10980 Human
FunctionThe protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. [provided by RefSeq, Jul 2008].
Related PathwayStem cell - PluripotencyDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY COPS6 (RC200252, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-COPS6.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-COPS6 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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