Home Antibody All anti-PSMA2 antibodies
Anti-PSMA2 TRUEMAB Antibody Clone 4D12
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for PSMA2 (NM_002787)
|Human recombinant protein fragment corresponding to amino acids 50-234 of human PSMA2(NP_002778) produced in E.coli.|
|Human , Dog , Rat , Monkey , Mouse
|| WB 1:200~2000,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 2 (PSMA2)|
|HC3; MU; PMSA2; PSC2|
Entrez Gene 5683 Human
Entrez Gene 19166 Mouse
Entrez Gene 29669 Rat
Entrez Gene 701683 Monkey
Entrez Gene 475870 Dog
|The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq, Jul 2008]. |
|ProteaseDruggable Genome Proteasome|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PSMA2 (RC208272, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PSMA2.
Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-PSMA2 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).