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Home Antibody All anti-DEF6 antibodies

Anti-DEF6 TRUEMAB Antibody Clone OTI4B5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA505353 DEF6 mouse monoclonal antibody, clone OTI4B5 (formerly 4B5) 100ul $325 In Stock
LC411815 DEF6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF505353 Carrier-free (BSA/glycerol-free) DEF6 mouse monoclonal antibody, clone OTI4B5 (formerly 4B5) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human DEF6(NP_071330) produced in HEK293T cell.
Clone NameClone OTI4B5 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:2000, IHC 1:150,
Predicted MW Explanation 73.7 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens differentially expressed in FDCP 6 homolog (mouse) (DEF6)
Alternative NameIBP; SLAT; SWAP70L
Database LinkNP_071330
Entrez Gene 50619 Human
FunctionDEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 [PubMed 12923183]).[supplied by OMIM].
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY DEF6 (RC217877, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-DEF6.
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Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-DEF6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA505353)
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