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Novel HIF2A mutations disrupt oxygen sensing, leading to polycythemia, paragangliomas, and somatostatinomas Blood, Mar 2013; 121: 2563 - 2566. [anti-HA]

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Home All anti-OTUB1 antibodies

Anti-OTUB1 TrueMAB Antibody Clone 2H1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA505158
  • Purified OTUB1 mouse monoclonal antibody,clone 2H1
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402607) , 20ug
100ul $325 In Stock Add to Shopping Cart
CF505158
  • Carrier-free (BSA/glycerol-free) OTUB1 mouse monoclonal antibody,clone 2H1
100ug $450 8-10 Days Add to Shopping Cart
WB(1)
IHC(9)
IF(1)
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Also for OTUB1 (NM_017670)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens OTU domain, ubiquitin aldehyde binding 1 (OTUB1), transcript variant 1
Synonyms:HSPC263; OTB1; OTU1
ImmunogenFull length human recombinant protein of human OTUB1(NP_060140) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone 2H1 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:2000, IHC 1:150, IF 1:100,
BackgroundThe product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY OTUB1 (RC210648, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-OTUB1.
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-OTUB1 mouse monoclonal antibody. (TA505158)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-OTUB1 mouse monoclonal antibody. (TA505158)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-OTUB1 mouse monoclonal antibody. (TA505158)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-OTUB1 mouse monoclonal antibody. (TA505158)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-OTUB1 mouse monoclonal antibody. (TA505158)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-OTUB1 mouse monoclonal antibody. (TA505158)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-OTUB1 mouse monoclonal antibody. (TA505158)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-OTUB1 mouse monoclonal antibody. (TA505158)
IHC Image
Immunohistochemical staining of paraffin-embedded Human bladder tissue using anti-OTUB1 mouse monoclonal antibody. (TA505158)
IF Image
Anti-OTUB1 mouse monoclonal antibody (TA505158) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY OTUB1(RC210648).

 

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