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Home Antibody All anti-RUNX1T1 antibodies

Anti-RUNX1T1 TRUEMAB Antibody Clone 1H1

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA504703
  • RUNX1T1 (ETO) mouse monoclonal antibody, Clone 1H1
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403575) , 20ug
100ul
30ul
379 In Stock
CF504703
  • Carrier-free (BSA/glycerol-free) RUNX1T1 mouse monoclonal antibody,clone 1H1
100ug $450 3-4 weeks
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WB(1)
IF(1)
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Also for RUNX1T1 (NM_175635)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human RUNX1T1(NP_783553) produced in HEK293T cell.
Clone NameClone 1H1 IsotypeIgG1
Species ReactivityHuman Concentration0.57mg/ml
Guaranteed Application *WB, IF Suggested DilutionsWB 1:2000, IF 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (RUNX1T1), transcript variant 3
Alternative NameAML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2
Database LinkNP_783553
FunctionThis gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RUNX1T1 (RC222426, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RUNX1T1.
IF Image
Anti-RUNX1T1 mouse monoclonal antibody (TA504703) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RUNX1T1(RC222426).

 

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