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Home Antibody All anti-ATIC antibodies

Anti-ATIC TRUEMAB Antibody Clone 1D2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA504553
  • ATIC mouse monoclonal antibody,clone 1D2
  • FREE positive control: HEK293T cell transient overexpression lysate (LC418255) , 20ug
100ul 379 In Stock
CF504553
  • Carrier-free (BSA/glycerol-free) ATIC mouse monoclonal antibody,clone 1D2
100ug $450 3-4 weeks
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WB(2)
FC(1)
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Also for ATIC (NM_004044)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human ATIC(NP_004035) produced in HEK293T cell.
Clone NameClone 1D2 IsotypeIgG1
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration0.71mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:500~2000, FLOW 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC)
Alternative NameAICAR; AICARFT; HEL-S-70p; IMPCHASE; PURH
Database LinkNP_004035
FunctionThis gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq].
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ATIC (RC203490, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ATIC.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-ATIC monoclonal antibody.
FC Image
HEK293T cells transfected with either RC203490 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-ATIC antibody(TA504553), and then analyzed by flow cytometry.

 

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