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Anti-CST3 TRUEMAB Antibody Clone OTI7G8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA504495 CST3 (Cystatin C) mouse monoclonal antibody, clone OTI7G8 (formerly 7G8) 100ul 325
In Stock
LC400040 CST3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504495 Carrier-free (BSA/glycerol-free) CST3 mouse monoclonal antibody, clone OTI7G8 (formerly 7G8) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human CST3(NP_000090) produced in HEK293T cell.
Clone NameClone OTI7G8 IsotypeIgG1
Species ReactivityHuman Concentration0.72 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:2000, FLOW 1:100,
Predicted MW Explanation 13.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cystatin C (CST3), transcript variant 1
Alternative NameARMD11
Database LinkNP_000090
Entrez Gene 1471 Human
FunctionThe cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. [provided by RefSeq].
Related PathwayES Cell Differentiation/IPSTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CST3 (RC210730, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CST3.
HEK293T cells transfected with either RC210730 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CST3 antibody(TA504495), and then analyzed by flow cytometry.


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