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Home Antibody All anti-SPG7 antibodies

Anti-SPG7 TRUEMAB Antibody Clone OTI1C12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA504420 SPG7 mouse monoclonal antibody, clone OTI1C12 (formerly 1C12) 100ul $325 In Stock
LC401085 SPG7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504420 Carrier-free (BSA/glycerol-free) SPG7 mouse monoclonal antibody, clone OTI1C12 (formerly 1C12) 100ug $450 4 Weeks
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WB(2)
IF(2)
FC(1)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 300-573 of human SPG7(NP_003110) prodduced in E.coli.
Clone NameClone OTI1C12 IsotypeIgG2a
Species ReactivityHuman, Mouse Concentration0.86 mg/ml
Guaranteed Application *WB, IF, FC Suggested DilutionsWB 1:500~2000, IF 1:50~100, FLOW 1:100,
Predicted MW Explanation 88.1 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameSPG7, paraplegin matrix AAA peptidase subunit
Alternative NameCAR|CMAR|PGN|SPG5C
Database LinkNP_003110
Entrez Gene 6687 Human
Entrez Gene 234847 Mouse
FunctionThis gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq].
Related PathwayTransmembraneProtease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.


WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPG7 (RC206340, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPG7.
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WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-SPG7 monoclonal antibody.
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IF Image
Anti-SPG7 mouse monoclonal antibody (TA504420) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SPG7(RC206340).
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IF Image
Immunofluorescent staining of HeLa cells using anti-SPG7 mouse monoclonal antibody (TA504420).
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FC Image
HEK293T cells transfected with either RC206340 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-SPG7 antibody(TA504420), and then analyzed by flow cytometry.
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