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Anti-RAMP2 TRUEMAB Antibody Clone OTI4E5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA504410 RAMP2 mouse monoclonal antibody, clone OTI4E5 (formerly 4E5) 100ul
In Stock
LC401774 RAMP2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504410 Carrier-free (BSA/glycerol-free) RAMP2 mouse monoclonal antibody, clone OTI4E5 (formerly 4E5) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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OriGene Data

ImmunogenFull length human recombinat protein of human RAMP2(NP_005845) produced in HEK293T cell.
Clone NameClone OTI4E5 IsotypeIgG1
Species ReactivityHuman Concentration1.25 mg/ml
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB 1:1000, IHC 1:150, FLOW 1:100,
Predicted MW Explanation 15.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens receptor (G protein-coupled) activity modifying protein 2 (RAMP2)
Alternative Name
Database LinkNP_005845
Entrez Gene 10266 Human
FunctionThe protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface. [provided by RefSeq].
Related PathwayTransmembraneDruggable Genome Vascular smooth muscle contraction

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RAMP2 (RC206531, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RAMP2.

IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-RAMP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504410)

FC Image
HEK293T cells transfected with either RC206531 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-RAMP2 antibody(TA504410), and then analyzed by flow cytometry.


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