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Home Antibody All anti-PSMB7 antibodies

Anti-PSMB7 TRUEMAB Antibody Clone OTI4E10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA504382 PSMB7 (Proteasome 20S beta 7 ) mouse monoclonal antibody, clone OTI4E10 (formerly 4E10) 100ul $325 In Stock
LC400993 PSMB7 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504382 Carrier-free (BSA/glycerol-free) PSMB7 mouse monoclonal antibody, clone OTI4E10 (formerly 4E10) 100ug $450 3-4 weeks
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WB(1)
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Also for PSMB7 (NM_002799)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 58-277 of human PSMB7(NP_002790) produced in E.coli.
Clone NameClone OTI4E10 IsotypeIgG1
Species ReactivityHuman Concentration0.37 mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:2000,
Predicted MW Explanation 29.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens proteasome (prosome, macropain) subunit, beta type, 7 (PSMB7)
Alternative NameZ
Database LinkNP_002790
Entrez Gene 5695 Human
FunctionThe proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. Expression of this catalytic subunit is downregulated by gamma interferon and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit). [provided by RefSeq].
Related PathwayProteaseDruggable Genome Proteasome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PSMB7 (RC201799, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PSMB7.
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