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Anti-CAMLG TRUEMAB Antibody clone 2H3
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for CAMLG (NM_001745)
|Full length human recombinant protein of human CAMLG(NP_001736) produced in HEK293T cell.|
|WB, IF, FC
|| WB 1:2000, IF 1:100, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens calcium modulating ligand (CAMLG)|
Entrez Gene 819 Human
|The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]. |
|Druggable Genome |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CAMLG (RC218292, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CAMLG.
Anti-CAMLG mouse monoclonal antibody (TA504363) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CAMLG(RC218292).
HEK293T cells transfected with either RC218292 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CAMLG antibody(TA504363), and then analyzed by flow cytometry.
Flow cytometric Analysis of Jurkat cells, using anti-CAMLG antibody(TA504363),(Red), compared to a nonspecific negative control antibody,(Blue).