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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-COPS5 antibodies

Anti-COPS5 TrueMAB Antibody Clone 2B12

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA504344
  • Purified COPS5 (JAB1) mouse monoclonal antibody, Clone 2B12
  • FREE positive control: HEK293T cell transient overexpression lysate (LC416392) , 20ug
 100ul $379 In Stock Add to Shopping Cart
CF504344
  • Carrier-free (BSA/glycerol-free) COPS5 mouse monoclonal antibody,clone 2B12
100ug $450 3-4 weeks Add to Shopping Cart
WB(1)
IHC(14)
IF(1)
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Also for COPS5 (NM_006837)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens COP9 signalosome subunit 5 (COPS5)
Synonyms:CSN5; JAB1; MOV-34; SGN5
ImmunogenFull length human recombinant protein of human COPS5(NP_006828) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone 2B12 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:2000, IHC 1:150, IF 1:100,
BackgroundThe protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq].
Related Pathway
TGF Beta Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY COPS5 (RC200979, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-COPS5.
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Ovary tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Human bladder tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-COPS5 mouse monoclonal antibody. (TA504344)
IHC Image
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-COPS5 mouse monoclonal antibody. (TA504344)
IF Image
Anti-COPS5 mouse monoclonal antibody (TA504344) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY COPS5(RC200979).

 

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