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 Home All anti-CYP2B6 antibodies

Anti-CYP2B6 TrueMAB Antibody clone 3D5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA504328
  • Purified CYP2B6 (Cytochrome P450 2B6) mouse monoclonal antibody, clone 3D5
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400259) , 20ug
 100ul $379 In Stock Add to Shopping Cart
CF504328
  • Carrier-free (BSA/glycerol-free) CYP2B6 mouse monoclonal antibody,clone 3D5
100ug $450 3-4 weeks Add to Shopping Cart
WB(2)
IHC(8)
IF(1)
FC(2)
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Also for CYP2B6 (NM_000767)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens cytochrome P450, family 2, subfamily B, polypeptide 6 (CYP2B6)
Synonyms:CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450
ImmunogenFull length human recombinant protein of human CYP2B6(NP_000758) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Nameclone 3D5 IsotypeIgG2a
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF, FC Suggested Dilutions WB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
BackgroundThis gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008].
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2B6 (RC217236, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2B6.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-CYP2B6 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CYP2B6 mouse monoclonal antibody. (TA504328)
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-CYP2B6 mouse monoclonal antibody. (TA504328)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CYP2B6 mouse monoclonal antibody. (TA504328)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-CYP2B6 mouse monoclonal antibody. (TA504328)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-CYP2B6 mouse monoclonal antibody. (TA504328)
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-CYP2B6 mouse monoclonal antibody. (TA504328)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-CYP2B6 mouse monoclonal antibody. (TA504328)
IHC Image
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-CYP2B6 mouse monoclonal antibody. (TA504328)
IF Image
Anti-CYP2B6 mouse monoclonal antibody (TA504328) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CYP2B6(RC217236).
FC Image
HEK293T cells transfected with either RC217236 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-CYP2B6 antibody(TA504328), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-CYP2B6 antibody(TA504328),(Red), compared to a nonspecific negative control antibody,(Blue).

 

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