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Home Antibody All anti-IDS antibodies

Anti-IDS TRUEMAB Antibody Clone OTI3B10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA504276 IDS (Iduronate 2 sulfatase) mouse monoclonal antibody, clone OTI3B10 (formerly 3B10) 100ul $325 In Stock
LC424863 IDS HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504276 Carrier-free (BSA/glycerol-free) IDS mouse monoclonal antibody, clone OTI3B10 (formerly 3B10) 100ug $450 3-4 weeks
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WB(2)
IHC(5)
IF(1)
FC(2)

OriGene Data

ImmunogenFull length human recombinant protein of human IDS(NP_000193) produced in HEK293T cell.
Clone NameClone OTI3B10 IsotypeIgG2a
Species ReactivityHuman Concentration0.79 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
Predicted MW Explanation 59.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens iduronate 2-sulfatase (IDS), transcript variant 1
Alternative NameMPS2; SIDS
Database LinkNP_000193
Entrez Gene 3423 Human
FunctionIduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq].
Related PathwayDruggable Genome Glycosaminoglycan degradationMetabolic pathwaysLysosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IDS (RC219187, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IDS.
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Western blot analysis of extracts (10ug) from 2 different cell lines by using anti-IDS monoclonal antibody at 1:200 dilution.
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-IDS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504276)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-IDS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504276)
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Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-IDS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504276)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-IDS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504276)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-IDS mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504276)
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Anti-IDS mouse monoclonal antibody (TA504276) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IDS(RC219187).
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Flow cytometric Analysis of Hela cells, using anti-IDS antibody(TA504276),(Red), compared to a nonspecific negative control antibody,(Blue).
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Flow cytometric Analysis of Jurkat cells, using anti-IDS antibody(TA504276),(Red), compared to a nonspecific negative control antibody,(Blue).
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