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Home Antibody All anti-RFXANK antibodies

Anti-RFXANK TRUEMAB Antibody Clone OTI3B4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA504263 RFXANK mouse monoclonal antibody, clone OTI3B4 (formerly 3B4) 100ul 325
In Stock
LC408725 RFXANK HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504263 Carrier-free (BSA/glycerol-free) RFXANK mouse monoclonal antibody, clone OTI3B4 (formerly 3B4) 100ug $450 3-4 weeks
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OriGene Data

ImmunogenFull length human recombinant protein of human RFXANK(NP_604389) produced in HEK293T cell.
Clone NameClone OTI3B4 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IF Suggested Dilutions WB 1:2000, IF 1:100,
Predicted MW Explanation 25.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens regulatory factor X-associated ankyrin-containing protein (RFXANK), transcript variant 2
Alternative NameANKRA1; BLS; F14150_1; RFX-B
Database LinkNP_604389
Entrez Gene 8625 Human
FunctionMajor histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Two transcript variants encoding different isoforms have been described for this gene, with only one isoform showing activation activity. [provided by RefSeq].
Related PathwayTranscription FactorsDruggable Genome Antigen processing and presentationPrimary immunodeficiency

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RFXANK (RC223081, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-RFXANK.

IF Image
Anti-RFXANK mouse monoclonal antibody (TA504263) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY RFXANK(RC223081).


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