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Home Antibody All anti-HES1 antibodies

Anti-HES1 TRUEMAB Antibody Clone OTI7B9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA504045 HES1 mouse monoclonal antibody, clone OTI7B9 (formerly 7B9) 100ul $325 In Stock
LC417251 HES1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF504045 Carrier-free (BSA/glycerol-free) HES1 mouse monoclonal antibody, clone OTI7B9 (formerly 7B9) 100ug $450 3 Days
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WB(2)
IHC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human HES1(NP_005515) produced in HEK293T cell.
Clone NameClone OTI7B9 IsotypeIgG1
Species ReactivityHuman, Monkey, Mouse, Rat Concentration0.88 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB 1:2000, IHC 1:150,
Predicted MW Explanation 29.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens hes family bHLH transcription factor 1 (HES1)
Alternative NamebHLHb39; HES-1; HHL; HRY
Database LinkNP_005515
Entrez Gene 3280 Human
Entrez Gene 15205 Mouse
Entrez Gene 29577 Rat
Entrez Gene 707140 Monkey
FunctionThis protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. [provided by RefSeq].
Related PathwayStem cell relevant signaling - DSL/Notch pathwayES Cell Differentiation/IPSAdult stem cellsCancer stem cellsTranscription FactorsDruggable Genome Notch signaling pathwayMaturity onset diabetes of the young

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HES1 (RC211709, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-HES1 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).(1:200)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-HES1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA504045)
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