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Home Antibody All anti-TIMP2 antibodies

Anti-TIMP2 TRUEMAB Antibody clone 3H8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA504042
  • TIMP2 mouse monoclonal antibody,clone 3H8
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418809) , 20ug
100ul 325 In Stock
CF504042
  • Carrier-free (BSA/glycerol-free) TIMP2 mouse monoclonal antibody,clone 3H8
100ug $450 3-4 weeks
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WB(1)
FC(1)
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Also for TIMP2 (NM_003255)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human TIMP2(NP_003246) produced in HEK293T cell.
Clone Nameclone 3H8 IsotypeIgG1
Species ReactivityHuman Concentration0.51 mg/ml
Guaranteed Application *WB, FC Suggested DilutionsWB 1:2000, FLOW 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens TIMP metallopeptidase inhibitor 2 (TIMP2)
Alternative NameCSC-21K; DDC8
Database LinkNP_003246
FunctionThis gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TIMP2 (RC209796, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TIMP2.
FC Image
HEK293T cells transfected with either RC209796 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-TIMP2 antibody(TA504042), and then analyzed by flow cytometry.

 

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