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Home Antibody All anti-CYP2A6 antibodies

Anti-CYP2A6 TRUEMAB Antibody clone 1D2

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503857
  • CYP2A6 (Cytochrome P450 2A6) mouse monoclonal antibody, clone 1D2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424530) , 20ug Explanation
100ul
30ul
379 In Stock
CF503857
  • Carrier-free (BSA/glycerol-free) CYP2A6 mouse monoclonal antibody,clone 1D2
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
This antibody qualifies for Season of Giving promotion: Earn $50 Amazon gift card (use promo code SPQ12081) or donation to Cancer.org (promo code SPQ12082) with $600 purchase of UltraMAB or TrueMAB. Click for details
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WB(2)
IHC(7)
FC(1)
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Also for CYP2A6 (NM_000762)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human CYP2A6(NP_000753) produced in HEK293T cell.
Clone Nameclone 1D2 IsotypeIgG2b
Species ReactivityHuman , Rat , Monkey , Mouse Concentration1.3 mg/ml
Guaranteed Application *WB, IHC, FC Suggested Dilutions WB 1:500~2000, IHC 1:150, FLOW 1:100,
Predicted MW Explanation 56.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens cytochrome P450, family 2, subfamily A, polypeptide 6 (CYP2A6)
Alternative NameCPA6; CYP2A; CYP2A3; CYPIIA6; P450C2A; P450PB
Database LinkNP_000753
Entrez Gene 1548 Human
FunctionThis gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq, Jul 2008].
Related PathwayTransmembraneP450Druggable Genome Caffeine metabolismRetinol metabolismDrug metabolism - cytochrome P450Drug metabolism - other enzymesMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP2A6 (RC222995, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP2A6.
WB Image
Western blot analysis of extracts (10ug) from 7 Human tissue by using anti-CYP2A6 monoclonal antibody ( 1: Uterus; 2: Breast; 3: Brain; 4: Liver; 5: Ovary; 6: Thyroid gland; 7: colon) at 1:200 dilution.
IHC Image
Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503857)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503857)
IHC Image
Immunohistochemical staining of paraffin-embedded Human endometrium tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503857)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503857)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503857)
IHC Image
Immunohistochemical staining of paraffin-embedded Human bladder tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503857)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-CYP2A6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503857)
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-CYP2A6 antibody(TA503857),(Red), compared to a nonspecific negative control antibody,(Blue).

 

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